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Cholesterol linoleate
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Cholesterol linoleate

CAS: 604-33-1

Ref. 3D-FC61959

2g
136.00 €
5g
195.00 €
10g
346.00 €
25g
678.00 €
50g
1,054.00 €
Estimated delivery in United States, on Thursday 19 Dec 2024

Product Information

Name:
Cholesterol linoleate
Controlled Product
Synonyms:
  • Linoleic Acid Cholesterol Ester
  • (3beta)-cholest-5-en-3-yl (9Z,12Z)-octadeca-9,12-dienoate
  • Cholest-5-en-3-ol (3β)-, (9Z,12Z)-9,12-octadecadienoate
  • Cholest-5-en-3-ol (3β)-, 3-[(9Z,12Z)-9,12-octadecadienoate]
  • Cholest-5-en-3-ol (3β)-, 9,12-octadecadienoate, (Z,Z)-
  • Linoleic acid, cholesteryl ester
  • NSC 18183
  • cholest-5-en-3-yl (9E,12E)-octadeca-9,12-dienoate
Description:

Cholesterol linoleate is a model system that is used to study the role of cholesterol in atherosclerosis. It consists of a cholesterol-based polymer and linoleic acid, which are chemically similar to the natural lipids found in human cells. In vitro studies have shown that this model system has an inhibitory effect on ATP binding cassette transporter A1 (ABCA1) and ABCG1. These proteins transport cholesterol from cellular membranes to other parts of the cell, where they are degraded by enzymes called lysosomes. Cholesterol linoleate also inhibits basic protein, an enzyme that breaks down cholesteryl, leading to reduced levels of cholesteryl esters in the atheromatous lesions. This model system has been shown to reduce disease activity in animals with atherosclerotic lesions.

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
649.08 g/mol
Formula:
C45H76O2
Color/Form:
White Powder
MDL:
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EINECS:
Merck:
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Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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