Costus lactone

CAS: 553-21-9

Ref. 3D-FC65612

Product Information

• Name: Costus lactone
• Synonyms: (+)-Costunolide, (3aS,10E,11aR)-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one, (3aS,6E,10E,11aR)-3a,4,5,8,9,11a-Hexahydro-6,10-dimethyl-3-methylenecyclodeca[b]furan-2(3H)-one, (3aS,6E,10E,11aR)-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one, (3aS,6Z,10E,11aR)-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one, Costunolid, Cyclodeca[b]furan-2(3H)-one, 3a,4,5,8,9,11a-hexahydro-6,10-dimethyl-3-methylene-, (3aS,6E,10E,11aR)-, Cyclodeca[b]furan-2(3H)-one, 3a,4,5,8,9,11a-hexahydro-6,10-dimethyl-3-methylene-, [3aS-(3aR*,6E,10E,11aS*)]-, Germacra-1(10),4,11(13)-trien-12-oic acid, 6α-hydroxy-, γ-lactone, (E,E)-, NSC 106404, Saussurea costus, Saussurea lappa, Costunolide

Description

Costus lactone is a natural compound that has been found to have potent anti-inflammatory properties. It is a diterpene ester and has been shown to have minimal toxicity in animal studies. Costulactone binds to the Bcl-2 protein, which prevents it from forming complexes with other proteins and inhibits the apoptosis pathway. It also inhibits the production of inflammatory cytokines such as tumor necrosis factor (TNF) and interleukin-1 (IL-1). Recent research has shown that costus lactone can act as an inhibitor of alcohol dehydrogenase, which may contribute to its anti-inflammatory properties.

• Brand: Biosynth

Chemical properties

• Molecular weight: 232.32 g/mol
• Formula: C₁₅H₂₀O₂
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/CH4/h1H4
• InChI key: InChIKey=VNWKTOKETHGBQD-UHFFFAOYSA-N
• SMILES: C#CC(=O)O[C@@H]1/C=C(\C)CC/C=C(\C)CCC1