Cyclovirobuxine D

CAS: 860-79-7

Ref. 3D-FC66624

Product Information

• Name: Cyclovirobuxine D
• Synonyms: (3beta,5alpha,9beta,16alpha,20S)-4,4,14-trimethyl-3,20-bis(methylamino)-9,19-cyclopregnan-16-ol, (3beta,5alpha,9xi,10xi,14xi,16alpha,20S)-4,4,14-trimethyl-3,20-bis(methylamino)-9,19-cyclopregnan-16-ol, (3α,5α,16α,20S)-4,4,14-Trimethyl-3,20-bis(methylamino)-9,19-cyclopregnan-16-ol, (3β,5α,16α,20S)-4,4,14-Trimethyl-3,20-bis(methylamino)-9,19-cyclopregnan-16-ol, 1H,19H-Cyclopropa[9,10]cyclopenta[a]phenanthrene, 9,19-cyclopregnan-16-ol deriv., 9,19-Cyclo-5α,9β-pregnan-16α-ol, 4,4,14-trimethyl-3β,20α-bis(methylamino)-, 9,19-Cyclopregnan-16-ol, 4,4,14-trimethyl-3,20-bis(methylamino)-, (3β,5α,16α,20S)-, Bebuxine, Cvb-D, Cyclovirobuxin D, Cyclovirobuxine, Cyclovirobuxinum D, NSC 91722

Description

Cyclovirobuxine D is a natural product that has been isolated from the stem bark of a Malaysian tree. It has shown synergistic effects with other compounds, such as cyclovirobuxine, in enhancing axonal growth and energy metabolism. Cyclovirobuxine D has also been shown to have a synergistic effect with cyclase inhibitors, such as rolipram and rolofylline, in the prevention of myocardial infarct. It blocks the cytosolic Ca2+ channel by binding to the ryanodine receptor and inhibiting Ca2+ release. The drug also inhibits glucose uptake in epithelial cells, which leads to cell death by apoptosis. Cyclovirobuxine D can be detected using analytical methods such as high-performance liquid chromatography (HPLC) or preparative HPLC.

• Brand: Biosynth

Chemical properties

• Molecular weight: 402.66 g/mol
• Formula: C₂₆H₄₆N₂O
• Purity: Min. 95%
• Color/Form: Powder