Product Information
Name:7-Chloroquinoxaline
Synonyms:
- 6-Chloroquinoxaline
Brand:Biosynth
Description:7-Chloroquinoxaline is a nucleophilic compound that can be synthesized by reductive chlorination of 7-chloroquinoline. 7-Chloroquinoxaline has been shown to have anticancer activity in vitro, as well as the ability to inhibit the proliferation of human breast cancer cells (MCF-7) in culture. It also inhibits glyoxalase I and II, which are enzymes that catalyze the conversion of glyoxal to D-lactate and H2O2. This inhibition may be due to its ability to react with the C=N bond at carbon 2 of dimethylformamide (DMF), forming a covalent adduct with DMF and an anticancer agent such as methotrexate or 5-fluorouracil. The formation of this conjugate would result in a decrease in DMF concentration, leading to decreased production of H2O2 and increased levels of D-l
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Chemical properties
Molecular weight:164.59 g/mol
Formula:C8H5ClN2
Purity:Min. 95%
InChI:InChI=1S/C8H5ClN2/c9-6-1-2-7-8(5-6)11-4-3-10-7/h1-5H
InChI key:InChIKey=HOOMNCITVCXDTR-UHFFFAOYSA-N
SMILES:Clc1ccc2nccnc2c1
Technical inquiry about: 7-Chloroquinoxaline
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