a-Cyanocinnamic acid

CAS: 1011-92-3

Ref. 3D-FC70296

Product Information

• Name: a-Cyanocinnamic acid
• Synonyms: alpha-Cyano-beta-phenylacrylic acid2-Cyano-3-phenyl-prop-2-enoic acid, (2E)-2-cyano-3-phenylprop-2-enoate, (2E)-2-cyano-3-phenylprop-2-enoic acid, (2Z)-2-cyano-3-phenylprop-2-enoic acid, 2-Cyano-3-phenyl-2-propenoic acid, 2-Cyano-3-phenylacrylic acid, 2-Cyanocinnamic acid, 2-Propenoic acid, 2-cyano-3-phenyl-, 3-Phenyl-2-cyano-2-propenoic acid, Benzylidene ethylcyanoacetane, Cinnamic acid, α-cyano-, Cyanocinnamicacid, NSC 298, α-Cyano-β-phenylacrylic acid, α-Cyanocinnamic acid

Description

a-Cyanocinnamic acid is a 3-hydroxycinnamic acid that can be found in coffee. It has been shown to inhibit the growth of colorectal adenocarcinoma cells and other cancer cells by binding to an inhibitor site on fatty acid synthesis enzymes, such as pyruvate carboxylase, hydroxylase, and acetyl-CoA carboxylase. This inhibition leads to decreased levels of fatty acids and increased levels of pyruvate and hydrogen peroxide, which inhibits cell proliferation. In addition, a-cyanocinnamic acid has been shown to have a hypoxic tumor selectivity index of 10.7%, which means it selectively targets tumors with low oxygen levels.

• Brand: Biosynth

Chemical properties

• Molecular weight: 173.17 g/mol
• Formula: C₁₀H₇NO₂
• Purity: Min. 95%
• Color/Form: White Powder