Columbianadin

CAS: 5058-13-9

Ref. 3D-FC73810

Product Information

• Name: Columbianadin
• Synonyms: 1-methyl-1-[(8S)-2-oxo-8,9-dihydro-2H-furo[2,3-h]chromen-8-yl]ethyl (2Z)-2-methylbut-2-enoate, 2-Butenoic acid, 2-methyl-, 1-(8,9-dihydro-2-oxo-2H-furo(2,3-h)-1-benzopyran-8-yl)-1-methylethyl ester, (S-(Z))-, 2-Butenoic acid, 2-methyl-, 1-[(8S)-8,9-dihydro-2-oxo-2H-furo[2,3-h]-1-benzopyran-8-yl]-1-methylethyl ester, (2Z)-, 2H-Furo[2,3-h]-1-benzopyran, 2-butenoic acid deriv., 2H-Furo[2,3-h]-1-benzopyran-2-one, 8,9-dihydro-8-(1-hydroxy-1-methylethyl)-, 2-methylcrotonate, (Z)-(S)-, Columbianedin, Columbianetin angelate, Columbianetin angelic ester, Crotonic acid, 2-methyl-, ester with 8,9-dihydro-8-(1-hydroxy-1-methylethyl)-2H-furo[2,3-h]-1-benzopyran-2-one, (Z)-(S)-, Zosimin

Description

Columbianadin is a natural drug that has been isolated from the roots of Pueraria lobata. Columbianadin is an inhibitor of cyclase, which inhibits protein kinase C (PKC) and inositol-1,4,5-trisphosphate receptor (IP3R). It also has anti-inflammatory and antifungal properties. In vitro experiments have shown that columbianadin inhibits HIV infection by targeting the ATP-dependent transport system. Columbianadin also shows antioxidant activity by inhibiting lipid peroxidation. This compound can be extracted from soybean extract using a concentration-time curve to determine the optimum extraction process. Columbianadin has been identified as a potent inhibitor of matrix metalloproteinases (MMPs). The physiological effects of columbianadin are not yet known.

• Brand: Biosynth

Chemical properties

• Molecular weight: 328.36 g/mol
• Formula: C₁₉H₂₀O₅
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C19H20O5/c1-5-11(2)18(21)24-19(3,4)15-10-13-14(22-15)8-6-12-7-9-16(20)23-17(12)13/h5-9,15H,10H2,1-4H3/b11-5-/t15-/m0/s1
• InChI key: InChIKey=JRIBPWOXWIRQOQ-GHAIFCDISA-N
• SMILES: C/C=C(/C)C(=O)OC(C)(C)[C@@H]1Cc2c(ccc3ccc(=O)oc23)O1