Calenduloside E

CAS: 26020-14-4

Ref. 3D-FC74357

Product Information

• Name: Calenduloside E
• Synonyms: (3β)-17-Carboxy-28-norolean-12-en-3-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid, 28-Desglucosylchikusetsusaponin IVa, 28-Noroleanane, b-D-glucopyranosiduronic acidderiv., 28-Noroleanane, β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid deriv., 3-O-(b-D-Glucopyranuronosyl)oleanolic acid, 3-O-(β-<span class="text-smallcaps">D</span>-Glucopyranuronosyl)oleanolic acid, 3-O-β-<span class="text-smallcaps">D</span>-Glucuronopyranosyloleanolic acid, 3β-Hydroxyolean-12-en-28-oic acid 3-O-β-<span class="text-smallcaps">D</span>-glucuronide, Glucopyranosiduronic acid, 3b-hydroxyolean-12-en-28-oic acid, b-D- (8CI), Glucopyranosiduronic acid, 3β-hydroxyolean-12-en-28-oic acid, β-<span class="text-smallcaps">D</span>-, Glycoside St-E, Momordin Ib, Olean-12-en-28-oic acid, 3β-(β-<span class="text-smallcaps">D</span>-glucopyranuronosyloxy)-, Olean-12-en-28-oicacid, 3b-(b-D-glucopyranuronosyloxy)- (8CI), Oleanolic acid 3-O-glucuronide, Oleanolic acid 3-O-β-<span class="text-smallcaps">D</span>-glucuronopyranoside, Oleanolic acid3-O-b-D-glucuronopyranoside, Polysciasaponin P7, Polysciasaponin P₇, Scheffleraside I, Silphioside F, β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, (3β)-17-carboxy-28-norolean-12-en-3-yl

Description

Calenduloside E is a lignan extracted from the Chinese herb, Calendula officinalis. It has been shown to have cardioprotective effects by restoring mitochondrial membrane potential and reducing oxidative damage in the myocardium following an ischemia-reperfusion injury. Calenduloside E also has anti-inflammatory properties, as it prevents lipopolysaccharide (LPS)-induced inflammatory response in mice. The ability of calenduloside E to prevent LPS-induced inflammation may be due to its inhibition of pro-inflammatory transcriptional factors such as NF-κB and AP-1. This compound also has antioxidant and anti-obesity effects, as it can inhibit lipid peroxidation and suppress weight gain in mice fed a high fat diet.

• Brand: Biosynth

Chemical properties

• Molecular weight: 632.82 g/mol
• Formula: C₃₆H₅₆O₉
• Purity: Min. 95%
• Color/Form: Powder