Chromone-3-carboxylic acid

Ref. 3D-FC75221

Product Information

• Name: Chromone-3-carboxylic acid
• Brand: Biosynth
• Description: Chromone-3-carboxylic acid is a reactive molecule that has been shown to exhibit antimicrobial properties. The three-dimensional structure of this molecule was first determined by vibrational spectroscopy, which showed that the hydroxy group and carbonyl group are in a hydrogen bond. Computational methods were used to determine the mechanism of reaction for chromone-3-carboxylic acid. This method showed that the presence of chloride ions or carbon disulphide could lead to the formation of a reactive intermediate. Chromone-3-carboxylic acid's cytostatic effects have been shown in both bacteria and mammalian cells, where it inhibits protein synthesis and induces apoptosis. Active methylene groups on chromone-3-carboxylic acid have also been shown to react with thiols, forming thioethers, which can act as inhibitors of enzymes such as phosphatases.

Chemical properties

• Molecular weight: 190.15 g/mol
• Formula: C₁₀H₆O₄
• Purity: Min. 95%
• InChI: InChI=1S/C10H6O4/c11-9-6-3-1-2-4-8(6)14-5-7(9)10(12)13/h1-5H,(H,12,13)
• InChI key: InChIKey=PCIITXGDSHXTSN-UHFFFAOYSA-N
• SMILES: O=C(O)c1coc2ccccc2c1=O