3,5-Di-tert-butyl-4-hydroxyanisole

CAS: 489-01-0

Ref. 3D-FD00075

Product Information

• Name: 3,5-Di-tert-butyl-4-hydroxyanisole
• Synonyms: 2,6-Di-tert-butyl-4-methoxyphenol
• Brand: Biosynth
• Description: 3,5-Di-tert-butyl-4-hydroxyanisole (BHT) is a chemical compound with the molecular formula C10H12O2. It is a white to yellowish waxy solid that is soluble in organic solvents and insoluble in water. BHT has been subjected to toxicity studies and found to have no acute toxic effects in rats, but does have potential for cardiac effects when administered at high doses. BHT has been shown to inhibit eugenol metabolism by competing with the enzyme flavonol glycoside hydroxylase, which leads to an increase of intracellular calcium levels and subsequent cardiac effects. This chemical also inhibits enzymes such as esterases, dehydrogenases, reductases, oxidases and transaminases. BHT also has been shown to inhibit uptake of radiolabeled drugs by rat liver microsomes and can be used as a kinetic probe for drug metabolism.

Chemical properties

• Molecular weight: 236.35 g/mol
• Formula: C₁₅H₂₄O₂
• Purity: Min. 96 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C15H24O2/c1-14(2,3)11-8-10(17-7)9-12(13(11)16)15(4,5)6/h8-9,16H,1-7H3
• InChI key: InChIKey=SLUKQUGVTITNSY-UHFFFAOYSA-N
• SMILES: COc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1