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3,4-Dichlorophenyl isocyanate

CAS:

Ref. 3D-FD00370

100g
134.00€
3,4-Dichlorophenyl isocyanate
Biosynth

Product Information

Name:3,4-Dichlorophenyl isocyanate
Brand:Biosynth
Description:3,4-Dichlorophenyl isocyanate is a reactive intermediate that features a hydroxyl group. 3,4-Dichlorophenyl isocyanate has been found to cause neurotoxicity in rats and mice by inhibiting the enzyme acetylcholinesterase (AChE) and causing an accumulation of acetylcholine (ACh). The activity of this molecule has been demonstrated using monoclonal antibodies against AChE. 3,4-Dichlorophenyl isocyanate reacts with lysine residues on proteins to form acrylate esters. This allows for the formation of crosslinks between proteins and DNA, which can lead to cancer.
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Chemical properties

Molecular weight:188.01 g/mol
Formula:C7H3Cl2NO
Purity:Min. 95%
Color/Form:Powder
InChI:InChI=1S/C7H3Cl2NO/c8-6-2-1-5(10-4-11)3-7(6)9/h1-3H
InChI key:InChIKey=MFUVCHZWGSJKEQ-UHFFFAOYSA-N
SMILES:O=C=Nc1ccc(Cl)c(Cl)c1

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