Diprenorphine

CAS: 14357-78-9

Ref. 3D-FD03511

Product Information

• Name: Diprenorphine
• Synonyms: (14Beta)-17-(Cyclopropylmethyl)-18-(2-Hydroxypropan-2-Yl)-6-Methoxy-18,19-Dihydro-4,5-Epoxy-6,14-Ethenomorphinan-3-Ol, (5alpha,6beta,14beta,18R)-17-(cyclopropylmethyl)-18-(2-hydroxypropan-2-yl)-6-methoxy-18,19-dihydro-4,5-epoxy-6,14-ethenomorphinan-3-ol, (5α,7α)-17-(Cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-6,14-ethenomorphinan-7-methanol, 1-N-Cyclopropylmethyl-6,7,8,14-tetrahydro-6,14-endoethano-7-(2′-hydroxy-2′-propyl)nororipavine, 21-Cyclopropyl-6,7,8,14-tetrahydro-7alpha-(1-hydroxy-1-methylethyl)-6,14-endo-ethanooripavine, 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha,alpha-dimethyl-, (5alpha,7alpha)-, 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-, (5α,7α)-, 6,14-endo-Ethanotetrahydrooripavine, 21-cyclopropyl-7α-(1-hydroxy-1-methylethyl)-, DEA No. 9058, Diprenorfina, Diprenorfina [INN-Spanish], Diprenorphine [INN:BAN], Diprenorphinum, Diprenorphinum [INN-Latin], M 5050, M 5050 Injection, M50-50, M50-50 Injection, N-(Cyclopropylmethyl)-19-methylnororvinol, Rx 5050M
• CAS: 14357-78-9

Description

Diprenorphine is a synthetic opioid drug that has low potency and high lipid solubility. It is an antagonist at the μ-opioid receptor and an agonist at the κ-opioid receptor. The hydroxyl group on the diprenorphine molecule affects its conformation, which may affect its ability to bind to the μ-opioid receptor. Diprenorphine binds competitively to the κ-opioid receptor, acting as a competitive inhibitor of morphine and other opiates. In addition, it can be used as a substrate for P-glycoprotein (P-gp), which is an important transporter for many drugs in the body. Diprenorphine is not clinically relevant as a pain reliever because it does not have any analgesic effects in humans or animals. Diprenorphine is also used as a radiolabeled probe for positron emission tomography (PET) imaging studies of P-gp activity

• Brand: Biosynth

Chemical properties

• Molecular weight: 425.56 g/mol
• Formula: C₂₆H₃₅NO₄
• Purity: Min. 95%
• Color/Form: Powder