Product Information
Name:DCC
Synonyms:
- 1,3-Dicyclohexyl carbodiimideN,N'-Dicyclohexylcarbodiimide
Brand:Biosynth
Description:DCC is a carbodiimide coupling reagent for amide and ester formation, used in peptide synthesis in presence of benzotriazole-based additives such as HOBt or HOAt to limit epimerisation. The urea by-product is highly insoluble in water and most organic solvents; therefore it can be easily removed by filtration. The insolubility of the urea makes the use of DCC unsuitable for solid-phase peptide synthesis unlike DIC, and only suitable for solution-phase couplings. Carbodiimide reagents including DCC tend to generate an N-acylurea by-product, whose formation can be controlled by forming the activated ester first and adding the amine afterwards, together with low reaction temperatures and the choice of DCM or chloroform as solvent.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:206.33 g/mol
Formula:C13H22N2
Purity:Min. 98 Area-%
Color/Form:Powder
InChI:InChI=1S/C13H22N2/c1-3-7-12(8-4-1)14-11-15-13-9-5-2-6-10-13/h12-13H,1-10H2
InChI key:InChIKey=QOSSAOTZNIDXMA-UHFFFAOYSA-N
SMILES:C(=NC1CCCCC1)=NC1CCCCC1
Technical inquiry about: DCC
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