5-(Difluoromethoxy)-2-mercaptobenzimidazole

CAS: 97963-62-7

Ref. 3D-FD05695

Product Information

• Name: 5-(Difluoromethoxy)-2-mercaptobenzimidazole
• Brand: Biosynth

Description

5-(Difluoromethoxy)-2-mercaptobenzimidazole is an organic solvent that is used in the crystallization process of pantoprazole, a benzimidazole derivative. It is also used as a corrosion inhibitor and pump inhibitor in analytical chemistry. The purity of 5-(difluoromethoxy)-2-mercaptobenzimidazole can be determined by chromatographic methods or by the use of analytical chemistry. Impurities may be genotoxic and include reactive impurities such as thiourea and 2-thiouracil. These impurities are removed during the synthetic process to produce 5-(difluoromethoxy)-2-mercaptobenzimidazole. This drug substance has been found to inhibit DNA polymerase activity in vitro, but its effects on human cells have not been studied.

Chemical properties

• Molecular weight: 216.21 g/mol
• Formula: C₈H₆F₂N₂OS
• Purity: Min. 95%
• Color/Form: Off-White Powder
• InChI: InChI=1S/C8H6F2N2OS/c9-7(10)13-4-1-2-5-6(3-4)12-8(14)11-5/h1-3,7H,(H2,11,12,14)
• InChI key: InChIKey=HJMVPNAZPFZXCP-UHFFFAOYSA-N
• SMILES: FC(F)Oc1ccc2[nH]c(=S)[nH]c2c1