2,6-Dichloropurine

CAS: 5451-40-1

Ref. 3D-FD06276

Product Information

• Name: 2,6-Dichloropurine
• Synonyms: 1H-Purine, 2,6-dichloro-, 2,6-Dichloro-1H-purine, 2,6-Dichloro-9H-purin, 2,6-dichloro-5H-purine, 2,6-dichloro-7H-purine, 2,6-dichloro-9H-purine, 9H-Purine, 2,6-dichloro-, NSC 18395, Purine, 2,6-dichloro-
• CAS: 5451-40-1

Description

2,6-Dichloropurine is a nitrogenous base that inhibits the activity of certain enzymes in the body. It has been shown to inhibit protease activity and nitro reductases, which are enzymes that metabolize nitrosamines. 2,6-Dichloropurine also inhibits the synthesis of epidermal growth factor (EGF) and adenosine A3 receptors in vivo. This drug has potent antitumor activity against various cancer cells and is used for the treatment of HIV infections. 2,6-Dichloropurine can be synthesized from 6-fluoro-3-indoxyl-beta-D-galactopyranoside with an intramolecular hydrogen atom.

• Brand: Biosynth

Chemical properties

• Molecular weight: 189 g/mol
• Formula: C₅H₂Cl₂N₄
• Purity: Min. 98 Area-%
• Color/Form: Powder
• InChI: InChI=1S/C5H2Cl2N4/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H,8,9,10,11)
• InChI key: InChIKey=RMFWVOLULURGJI-UHFFFAOYSA-N
• SMILES: Clc1nc(Cl)c2[nH]cnc2n1