1,2,4-Dithiazolidine-3,5-dione

CAS: 35371-97-2

Ref. 3D-FD07161

Product Information

• Name: 1,2,4-Dithiazolidine-3,5-dione
• Synonyms: DtsNH
• Brand: Biosynth
• Description: 1,2,4-Dithiazolidine-3,5-dione is a disulfide bond compound that contains a nucleophilic cysteine residue. It is oxidized to the corresponding sulfoxide or sulfone by reaction with hydrochloric acid. 1,2,4-Dithiazolidine-3,5-dione has been shown to react with amines to form adducts. The nucleophilic attack of the sulfur atom on the carbonyl carbon generates an intermediate thioketal and leaves the original disulfide intact. The nucleophilic attack leads to a number of possible products including dithioesters and dithioimidates. Both these products are stable in water and can be used in organic synthesis reactions such as DNA duplex formation.

Chemical properties

• Molecular weight: 135.16 g/mol
• Formula: C₂HNO₂S₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C2HNO2S2/c4-1-3-2(5)7-6-1/h(H,3,4,5)
• InChI key: InChIKey=BPVALDZRWMHTCJ-UHFFFAOYSA-N
• SMILES: O=c1[nH]c(=O)ss1