Product Information
- N-[(3R,4S)-3,4-Dihydro-3-[[(methylamino)carbonyl]oxy]-6-[4-(3-oxetanyl)-1-piperazinyl]-2H-1-benzopyran-4-yl]-4-fluorobenzamide
LY 3000328 is a small molecule that inhibits the activation of pro-apoptotic proteins. It has been shown to induce apoptotic cell death in cancer cells. LY 3000328 also induces autophagy and enhances the activity of chaperones, which are proteins that help other proteins fold correctly. The drug inhibits the phosphatase PP2A, which is involved in many cellular processes, including cytosolic calcium regulation. LY 3000328 was found to have no effect on endoplasmic reticulum or ryanodine receptor function. This inhibition may be due to its ability to bind with ATP and inhibit its hydrolysis by PP2A.
Chemical properties
Technical inquiry about: 3D-FD103542 LY 3000328
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