(2S,6R)-2,6-Diaminoheptanedioic acid
CAS: 922-54-3
Ref. 3D-FD106384
1mg | 149.00 € | ||
2mg | 206.00 € | ||
5mg | 330.00 € | ||
10mg | 484.00 € | ||
25mg | 689.00 € |
Product Information
- Heptanedioicacid, 2,6-diamino-, (R*,S*)-
- Heptanedioic acid, 2,6-diamino-, meso- (8CI)
- Nsc206289
- meso-2,6-Diaminopimelic acid
- meso-a,a'-Diaminopimelic acid
- meso-a,e-Diaminopimelic acid
- (2R,6S)-2,6-diaminoheptanedioic acid
- heptanedioic acid, 2,6-diamino-, (2R,6S)-
(2S,6R)-2,6-Diaminoheptanedioic acid is an antimicrobial agent that inhibits bacterial growth by binding to the Toll-like receptor 2 (TLR2) and Toll-like receptor 4 (TLR4). It has been shown to inhibit the production of IL-12 in a dose-dependent manner. The crystal structure of the complex between (2S,6R)-2,6-diaminoheptanedioic acid and TLR4 reveals that this compound binds to TLR4 at the interface between its extracellular domain and transmembrane domain, which disrupts the interaction between TLR4 and its ligands. This compound also inhibits calcium uptake by gram-positive bacteria such as Staphylococcus aureus and Enterococcus faecalis. (2S,6R)-2,6-Diaminoheptanedioic acid may be used for wastewater treatment because it
Chemical properties
Technical inquiry about: 3D-FD106384 (2S,6R)-2,6-Diaminoheptanedioic acid
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