(Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt

CAS: 500170-27-4

Ref. 3D-FD109768

Product Information

• Name: (Deamino-Cys1,b-cyclohexyl-Ala4,Arg8)-Vasopressin trifluoroacetate salt
• Synonyms: (Deamino-Cys¹,Cha?,Arg?)-Vasopressin3-Mercaptopropionyl-Tyr-Phe-?-cyclohexyl-Ala-Asn-Cys-Pro-Arg-Gly-NH2 trifluoroacetate salt (Dis ulfide bond)
• Brand: Biosynth
• Description: Desmopressin is a synthetic analogue of vasopressin, which is used to treat disorders associated with insufficient secretion of vasopressin. It has been shown that desmopressin binds to the vasopressin V2 receptor subtype and stimulates the release of arginine-vasopressin in corticotropin-releasing hormone (CRH)-treated rat pituitary cells. This stimulation was mediated by a residue on the Cys1,b-cyclohexyl residue. The binding of desmopressin to this site was demonstrated in vitro using binding experiments on rat brain synaptosomes. Desmopressin has also been shown to stimulate ovulation in rats and humans, and it has been shown to be effective for treating nocturnal enuresis in children.

Chemical properties

• Molecular weight: 1,094.31 g/mol
• Formula: C₅₀H₇₁N₁₃O₁₁S₂
• Purity: Min. 95%