Dansyl-Glu-Gly-Arg-chloromethylketone
CAS: 69024-84-6
Ref. 3D-FD111116
| 1mg | 181.00 € | ||
| 2mg | 315.00 € | ||
| 5mg | 527.00 € | ||
| 10mg | 872.00 € | ||
| 25mg | 1,783.00 € |
Product Information
- Glycinamide,N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-L-a-glutamyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-(9CI)
- Glycinamide, N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-L-a-glutamyl-N-[4-[(aminoiminomethyl)amino]-1-(chloroacetyl)butyl]-,(S)-
- Dansylglutamyl-Glycyl-Arginine Chloromethyl Ketone
Dansyl-Glu-Gly-Arg-chloromethylketone is a fluorescent substrate for epidermal growth factor (EGF). It has been shown to inhibit the proteolytic activity of EGF. This inhibition is due to the binding of Dansyl-Glu-Gly-Arg-chloromethylketone to calcium and its inhibitory properties on EGF. The flow system used in this experiment was activated with a monoclonal antibody, which binds to the cytosolic calcium and activates the enzyme. The kinetic data obtained from this experiment showed that the rate of EGF hydrolysis by Dansyl-Glu-Gly-Arg-chloromethylketone was proportional to the concentration of calcium in the cytosol.
Chemical properties
Technical inquiry about: 3D-FD111116 Dansyl-Glu-Gly-Arg-chloromethylketone
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