2-(2,4-Dichlorophenoxy)acetohydrazide

CAS: 28236-62-6

Ref. 3D-FD114190

Product Information

• Name: 2-(2,4-Dichlorophenoxy)acetohydrazide
• Synonyms: 2-(2,4-Dichlorophenoxy)Acetohydrazide, Akos Bbs-00000671, Labotest-Bb Lt00019836, Timtec-Bb Sbb000731, -2,4-DICHLOROPHENOXYACETIC ACID HYDRAZIDE

Description

2-(2,4-Dichlorophenoxy)acetohydrazide (2,4-DAH) is a phenacyl analogue that has been shown to have anti-cancer and anti-inflammatory activities. It inhibits the cyclooxygenase enzyme, which is involved in the synthesis of prostaglandins. This inhibition leads to a decrease in production of inflammatory mediators such as prostaglandin E2 and leukotriene B4. 2,4-DAH also potently inhibits human fibroblast cells and cancer cells with IC50 values of 3.7 μM and 10 μM respectively. The most common side effects are nausea, vomiting, headache, dizziness, lightheadedness, and diarrhea.

• Brand: Biosynth

Chemical properties

• Molecular weight: 235.07 g/mol
• Formula: C₈H₈Cl₂N₂O₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C8H8Cl2N2O2/c9-5-1-2-7(6(10)3-5)14-4-8(13)12-11/h1-3H,4,11H2,(H,12,13)
• InChI key: InChIKey=OEYOIIKYUVBUJN-UHFFFAOYSA-N
• SMILES: NNC(=O)COc1ccc(Cl)cc1Cl