4,6-Dichloro-2-methylpyrimidine

CAS: 1780-26-3

Ref. 3D-FD11549

Product Information

• Name: 4,6-Dichloro-2-methylpyrimidine
• Brand: Biosynth
• Description: 2-Chloro-6-methylaniline is a synthetic compound that has been used in the synthesis of medicines, such as dasatinib. It is a nucleophile that binds to the receptor site on cells and blocks the binding of natural hormones. It is also an inhibitor of certain enzymes, including RNA polymerase and protein kinase. 2-Chloro-6-methylaniline is industrially produced by reacting sodium chloride with chlorosulfonic acid or hydrochloric acid in an autoclave at a temperature of 180 °C for three hours. The product can be purified by adding magnesium oxide and activated with hydrochloric acid to form 2-chloro-6-methylpyrimidine. The main impurities are 4,6-dichloro2 methylpyrimidine and 6,8 dichloro2 methylpyrimidine.

Chemical properties

• Molecular weight: 163 g/mol
• Formula: C₅H₄Cl₂N₂
• Purity: Min. 95%
• Color/Form: White To Yellow Solid