3-(2,5-Dioxoimidazolidin-4-yl)propanoic acid

CAS: 5624-26-0

Ref. 3D-FD118157

Product Information

• Name: 3-(2,5-Dioxoimidazolidin-4-yl)propanoic acid
• Synonyms: 2,5-Dioxo-4-imidazolidinepropanoic acid, 3-(2,4-Dioxoimidazolidin-5-yl)propanoic acid, 3-(2,5-Dioxo-4-imidazolidinyl)propanoic acid, 3-(2,5-Dioxo-4-imidazolidinyl)propans?ure, 4-Imidazolidinepropanoic acid, 2,5-dioxo-, 4-Imidazolidinepropionic acid, 2,5-dioxo-, 5-Hydantoinpropionic acid, <span class="text-smallcaps">DL</span>-5-(2-Carboxyethyl)hydantoin, Acide 3-(2,5-dioxo-4-imidazolidinyl)propano?que, NSC 23606

Description

3-(2,5-Dioxoimidazolidin-4-yl)propanoic acid (3DAP) is a histidine analog that belongs to the group of fatty acid derivatives. It has been shown to be effective in the diagnosis of obesity and provides a new approach for the treatment of obesity. 3DAP binds to organic anion transporters, which are proteins that transport organic anions across cell membranes. This binding inhibits the transport of organic anion substrates and leads to increased concentrations of these substrates in blood plasma. 3DAP is a competitive inhibitor against estrone sulfate, which is one of its major metabolites. 3DAP has shown efficacy in animal models for obesity, diabetes, and hepatic steatosis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 172.14 g/mol
• Formula: C₆H₈N₂O₄
• Purity: Min. 95%
• InChI: InChI=1S/C6H8N2O4/c9-4(10)2-1-3-5(11)8-6(12)7-3/h3H,1-2H2,(H,9,10)(H2,7,8,11,12)
• InChI key: InChIKey=VWFWNXQAMGDPGG-UHFFFAOYSA-N
• SMILES: O=C(O)CCC1NC(=O)NC1=O