4,6-Dimethyl-2-hydroxypyrimidine

CAS: 108-79-2

Ref. 3D-FD12054

Product Information

• Name: 4,6-Dimethyl-2-hydroxypyrimidine
• Synonyms: 2-Hydroxy-4,6-dimethylpyrimidinec, 2(1H)-Pyrimidinone, 4,6-dimethyl-, 2(1H)-Pyrimidone, 4,6-dimethyl-, 2-Hydroxy-4,6-dimethylpyrimidine, 2-Pyrimidinol, 4,6-dimethyl-, 4,6-Dimethyl-1,2-dihydro-2-pyrimidone, 4,6-Dimethyl-1,2-dihydropyrimidin-2-one, 4,6-Dimethyl-2(1H)-Pyrimidinon, 4,6-Dimethyl-2(1H)-pyrimidinone, 4,6-Dimethyl-2(1H)-pyrimidone, 4,6-Dimethyl-2(3H)-pyrimidinone, 4,6-Dimethyl-2-pyrimidone, 4,6-dimethyl-2-PYRIMIDINOL, 4,6-dimethylpyrimidin-2(1H)-one, 4,6-dimethylpyrimidin-2-OL

Description

4,6-Dimethyl-2-hydroxypyrimidine (DMHP) is an antibiotic drug that inhibits the activity of lipoprotein lipase. DMHP is a broad-spectrum antibiotic that has been shown to have inhibitory effects on bacterial growth in vitro assays. The chemical ionization method was used to measure the amount of DMHP in plasma samples. Results showed that DMHP levels were below the limit of detection in all samples. This suggests that DMHP does not accumulate in the body and may be metabolized quickly. Liquid chromatography with ultra violet light detection was used to analyze the chemical structure of DMHP and found it to be a mixture of two compounds: 4,6-dimethylpyrimidin-2(1H)-one and 2,4,6-trimethoxypyrimidine. The surface methodology was used to identify target tissues for toxicity studies, showing that this compound preferentially binds to liver tissue.

• Brand: Biosynth

Chemical properties

• Molecular weight: 124.14 g/mol
• Formula: C₆H₈N₂O
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C6H8N2O/c1-4-3-5(2)8-6(9)7-4/h3H,1-2H3,(H,7,8,9)
• InChI key: InChIKey=WHEQVHAIRSPYDK-UHFFFAOYSA-N
• SMILES: Cc1cc(C)[nH]c(=O)n1