2-(Dimethylamino)nicotinonitrile
CAS: 60138-76-3
Ref. 3D-FD121666
| 1g | To inquire | ||
| 2g | To inquire | ||
| 5g | To inquire | ||
| 250mg | To inquire | ||
| 500mg | To inquire |
Product Information
- 3-pyridinecarbonitrile
- 2-(dimethylamino)-
- 3-Pyridinecarbonitrile, 2-(Dimethylamino)-
2-(Dimethylamino)nicotinonitrile is a precursor for the synthesis of aminopyridines. It is prepared by diazotizing 2-amino-5-nitropyridine with sodium nitrite in concentrated hydrochloric acid, followed by addition of dimethylformamide and trifluoromethanesulfonic acid. The reaction yields 2-(dimethylamino)nicotinonitrile, as well as other products including 2-methylpiperidine and 4-methylpiperidine. This process can be improved by using microwaves or a catalyst such as trifluoromethanesulfonic anhydride or trifluoroacetic anhydride.
2-(Dimethylamino)nicotinonitrile is used to synthesize aminopyridines, which are intermediates in the production of various medications such as antibiotics and cancer drugs.
Chemical properties
Technical inquiry about: 3D-FD121666 2-(Dimethylamino)nicotinonitrile
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