2-(Dimethylamino)nicotinonitrile

Ref. 3D-FD121666

Product Information

• Name: 2-(Dimethylamino)nicotinonitrile
• Synonyms: 3-pyridinecarbonitrile, 2-(dimethylamino)-
• Brand: Biosynth
• Description: 2-(Dimethylamino)nicotinonitrile is a precursor for the synthesis of aminopyridines. It is prepared by diazotizing 2-amino-5-nitropyridine with sodium nitrite in concentrated hydrochloric acid, followed by addition of dimethylformamide and trifluoromethanesulfonic acid. The reaction yields 2-(dimethylamino)nicotinonitrile, as well as other products including 2-methylpiperidine and 4-methylpiperidine. This process can be improved by using microwaves or a catalyst such as trifluoromethanesulfonic anhydride or trifluoroacetic anhydride.; 2-(Dimethylamino)nicotinonitrile is used to synthesize aminopyridines, which are intermediates in the production of various medications such as antibiotics and cancer drugs.

Chemical properties

• Molecular weight: 147.18 g/mol
• Formula: C₈H₉N₃
• Purity: Min. 95%