Dimethyl 2,2'-thiodiacetate

Ref. 3D-FD133308

Product Information

• Name: Dimethyl 2,2'-thiodiacetate
• Synonyms: acetic acid, 2,2'-thiobis-, dimethyl ester
• Brand: Biosynth
• Description: Dimethyl 2,2'-thiodiacetate is a chemical crosslinking agent that reacts with the thiol group of proteins and peptides. It is used as a diagnostic reagent for neurodegenerative diseases. Dimethyl 2,2'-thiodiacetate binds to nitrogen atoms in the amino acid tyrosine, forming an alkylthio-tyrosine complex that inhibits the activity of the tyrosine kinase enzyme. This results in reduced synthesis of proteins containing tyrosine residues.

Chemical properties

• Molecular weight: 178.21 g/mol
• Formula: C₆H₁₀O₄S
• Purity: Min. 95%
• InChI: InChI=1S/C6H10O4S/c1-9-5(7)3-11-4-6(8)10-2/h3-4H2,1-2H3
• InChI key: InChIKey=ZQUQLLPRRJVUES-UHFFFAOYSA-N
• SMILES: COC(=O)CSCC(=O)OC