Diethyl (5-phenylisoxazol-3-yl) phosphate

CAS: 32306-29-9

Ref. 3D-FD140576

Product Information

• Name: Diethyl (5-phenylisoxazol-3-yl) phosphate
• Brand: Biosynth
• Description: Diethyl (5-phenylisoxazol-3-yl) phosphate is a chlorpyrifos analog that is detectable in the blood and urine. The compound has been detected in red blood cells, plasma, serum, and urine samples at levels of 10 to 50 μg/L. Diethyl (5-phenylisoxazol-3-yl) phosphate can be used as an analytical method for detecting chlorpyrifos residue on food products or in environmental samples. Diethyl (5-phenylisoxazol-3-yl) phosphate is transfected into human hepatoma cells and activated by carbamate or propanil. It inhibits cellular protein synthesis by binding to the 30S ribosomal subunit, preventing the formation of the initiation complex between aminoacyl tRNA and mRNA. This binding also prevents peptide bond formation between amino acids, leading to cell death.

Chemical properties

• Molecular weight: 297.24 g/mol
• Formula: C₁₃H₁₆NO₅P
• Purity: Min. 95%
• InChI: InChI=1S/C13H16NO5P/c1-3-16-20(15,17-4-2)19-13-10-12(18-14-13)11-8-6-5-7-9-11/h5-10H,3-4H2,1-2H3
• InChI key: InChIKey=VLBRWDJSOHOVGF-UHFFFAOYSA-N
• SMILES: CCOP(=O)(OCC)Oc1cc(-c2ccccc2)on1