2,2'-(Diazene-1,2-diyl)bis(2-methylpropanimidamide) dihydrochloride

CAS: 2997-92-4

Ref. 3D-FD142593

Product Information

• Name: 2,2'-(Diazene-1,2-diyl)bis(2-methylpropanimidamide) dihydrochloride
• Synonyms: 2,2'-Azobis(2-methylpropionamide)dihydrochloride, 2,2'-Azobis(isobutyramidine hydrochloride), 2,2'-Azobis(propane-2-carboxamidine) dihydrochloride, 2,2'-Azobis-(2-amidinopropane) dihydrochloride, 2,2'-Azobis[2-Metilpropionamidina], Diclorhidrato, 2,2'-Azobis[2-methylpropionamidin]dihydrochlorid, 2,2'-Azobis[2-methylpropionamidine], dichlorhydrate, 2,2'-Azobisamidinopropane dihydrochloride, 2,2'-Azobisisobutyramidinium chloride, 2,2-Azobis(2-Methylpropionamidine)Dihydrochlorid, 2,2′-(Diazene-1,2-diyl)bis(2-methylpropanimidamide) dihydrochloride, 2,2′-Azobis(isobutyramidine) dihydrochloride, 2,2′-Azodiisobutylamidine dihydrochloride, 2,2′-Azodiisobutyramidine dihydrochloride, 2-(2-Amino-2-Imino-1,1-Dimethyl-Ethyl)Azo-2-Methyl-Propanamidine Dihydrochloride, Aaph, Aiba, Azo two isobutyl Acetamiprid hydrochloride, Azobis(isobutyl)amidine hydrochloride, Azobis(isobutyramidine) dihydrochloride, Azobisisobutyramidinium dichloride, Azostarter V 50, Dn 55549, MS 1 (catalyst), Ms 1, Nc 32P, Propanimidamide, 2,2'-(1,2-diazenediyl)bis[2-methyl-, hydrochloride (1:2), Propanimidamide, 2,2'-azobis[2-methyl-, dihydrochloride, Propionamidine, 2,2'-azobis[2-methyl-, dihydrochloride, TB 2000 (initiator), Tb 2000, V 50, V 50 initiator, V50, VA 50 (catalyst), Va 050, Va 50, Vazo 55, Vazo 56, Vazo 56WSP, Vazo 56WSW, Wako V 50

Description

2,2'-(Diazene-1,2-diyl)bis(2-methylpropanimidamide) dihydrochloride (BPDC) is a synthetic compound that is used as an analytical reagent and a model system for oxidative injury. It has significant cytotoxicity on human cells in cell culture. BPDC induces oxidative damage to proteins and DNA by increasing the production of reactive oxygen species such as hydrogen peroxide, superoxide, and hydroxyl radicals. The mechanism of action is not well understood but may be due to Toll-like receptor signalling pathways. This compound has been shown to inhibit the activity of antioxidant enzymes such as glutathione peroxidase and catalase. It also inhibits the activity of proinflammatory cytokines such as IL-6 and IL-8. BPDC is being investigated for its potential use in bowel disease treatment.

• Brand: Biosynth

Chemical properties

• Molecular weight: 271.19 g/mol
• Formula: C₈H₂₀Cl₂N₆
• Purity: Min. 95%
• Color/Form: Powder