(2,2-Dimethyl-1,3-dioxan-5-yl)methanol

CAS: 4728-12-5

Ref. 3D-FD144048

Product Information

• Name: (2,2-Dimethyl-1,3-dioxan-5-yl)methanol
• Synonyms: 1,3-Dioxane-5-methanol, 2,2-dimethyl-, 2,2-Dimethyl-1,3-dioxane-5-methanol, 2,2-Dimethyl-5-hydroxymethyl-1,3-dioxane, [2,2-Dimethyl-1,3-dioxan-5-yl)methanol, m-Dioxane-5-methanol, 2,2-dimethyl-

Description

(2,2-Dimethyl-1,3-dioxan-5-yl)methanol is a nucleotide that is structurally related to 2-amino-6-chloropurine. It has been shown to inhibit the incorporation of uracil into dsDNA and to act as a competitive inhibitor of adefovir and bisphosphonates. (2,2-Dimethyl-1,3-dioxan-5-yl)methanol inhibits phosphorylation by methylation of the hydroxyl group on the C5 position of the sugar moiety. This reaction results in an alkylated sugar with a phosphite group at the C5 position. The resulting product can undergo chloromethylation, which generates an additional reactive site for covalent modifications such as acetalization or esterification.

• Brand: Biosynth

Chemical properties

• Molecular weight: 146.18 g/mol
• Formula: C₇H₁₄O₃
• Purity: Min. 95%
• Color/Form: Clear Liquid