(2,2-Dimethyl-1,3-dioxan-5-yl)methanol

CAS: 4728-12-5

Ref. 3D-FD144048

Product Information

• Name: (2,2-Dimethyl-1,3-dioxan-5-yl)methanol
• Brand: Biosynth
• Description: (2,2-Dimethyl-1,3-dioxan-5-yl)methanol is a nucleotide that is structurally related to 2-amino-6-chloropurine. It has been shown to inhibit the incorporation of uracil into dsDNA and to act as a competitive inhibitor of adefovir and bisphosphonates. (2,2-Dimethyl-1,3-dioxan-5-yl)methanol inhibits phosphorylation by methylation of the hydroxyl group on the C5 position of the sugar moiety. This reaction results in an alkylated sugar with a phosphite group at the C5 position. The resulting product can undergo chloromethylation, which generates an additional reactive site for covalent modifications such as acetalization or esterification.

Chemical properties

• Molecular weight: 146.18 g/mol
• Formula: C₇H₁₄O₃
• Purity: Min. 95%
• Color/Form: Clear Liquid