Dextromethorphan hydrobromide

CAS: 125-69-9

Ref. 3D-FD146330

Product Information

• Name: Dextromethorphan hydrobromide
• Synonyms: (+)-3-Methoxy-17-methyl-morphinan hydrobromide, (9Alpha,13Alpha,14Alpha)-3-Methoxy-17-Methylmorphinan Hydrobromide, (9Alpha,13Alpha,14Alpha)-3-Methoxy-17-Methylmorphinan Hydrobromide Hydrate, 3-Methoxy-17-Methylmorphinan Hydrobromide, 9α,13α,14α-Morphinan, 3-methoxy-17-methyl-, hydrobromide, Alpha-dextromethorphan, Antussan, Codiphan, Coldex-D, Colfed, Delsym, Demorphan, Demorphine, Destromethorphan hydrobromide, Detosiv Slow Release, Dextromethorphan bromide, Dextromethorphan maleate HBR, Dextroramin P, Dormetan, Dormethan, Medicon, Methorate hydrobromide, Metrorat, Morphinan, 3-methoxy-17-methyl-, hydrobromide (1:1), (9α,13α,14α)-, Morphinan, 3-methoxy-17-methyl-, hydrobromide, (9α,13α,14α)-, Nocuf, Ro 1-5470, Romilar, Tosse Sedativo, Tusilan, Tussade, d-3-Methoxy-N-methylmorphinan hydrobromide, d-Methorphan hydrobromide, dextromethorphan HBR

Description

Dextromethorphan hydrobromide is a drug that has been used to treat cough and cold symptoms. It is also an NMDA receptor antagonist, which blocks the activity of the NMDA receptor. Dextromethorphan hydrobromide is metabolized by the liver into dextrorphan and 3-methoxymorphinan, which are both active metabolites. Dextrorphan is a more potent NMDA receptor antagonist than dextromethorphan. The elimination half-life for dextrorphan is about 2 hours, whereas the elimination half-life for dextromethorphan is about 8 hours. The concentration-time curve for dextrorphan has been shown to be sigmoidal with a long tail, whereas the concentration-time curve for dextromethorphan has been shown to be linear with no long tail. Dextrorphan binds to adenosine A3 receptors in a competitive manner and has been shown

• Brand: Biosynth

Chemical properties

• Molecular weight: 352.31 g/mol
• Formula: C₁₈H₂₅NO·HBr
• Purity: Min. 95%