Desmethyl rabeprazolethioether

Ref. 3D-FD150272

Product Information

• Name: Desmethyl rabeprazolethioether
• Brand: Biosynth
• Description: Rabeprazole is a proton pump inhibitor (PPI) that inhibits the secretion of stomach acid. It is a racemic mixture of two enantiomers, desmethyl rabeprazole and thiomethyl rabeprazole. The pharmacokinetics of rabeprazole have been determined in healthy Chinese subjects and in human urine using liquid chromatography-mass spectrometry (LC-MS). These experiments showed that desmethyl rabeprazole has a longer half-life than thiomethyl rabeprazole. In addition, the LC-MS parameters were used to calculate the pharmacokinetic parameters of both enantiomers. Rabeprazole has been shown to inhibit donepezil metabolism, which may result in an increased exposure to donepezil.

Chemical properties

• Molecular weight: 329.42 g/mol
• Formula: C₁₇H₁₉N₃O₂S
• Purity: Min. 95%