Di-tert-butylchlorophosphine

CAS: 13716-10-4

Ref. 3D-FD152848

Product Information

• Name: Di-tert-butylchlorophosphine
• Synonyms: Bis(1,1-dimethylethyl)phosphinous chloride, Bis(tert-butyl)chlorophosphine, Bis(tert-butyl)phosphinous chloride, Chlorodi-tert-butylphosphine, Di-Tert-Butylphosphinous Chloride, Di-t-butylchlorophosphine, Di-tert-butylchlorophosphane, P,P-Bis(1,1-dimethylethyl)phosphinous chloride, Phosphinous chloride, P,P-bis(1,1-dimethylethyl)-, Phosphinous chloride, bis(1,1-dimethylethyl)-, Phosphinous chloride, di-tert-butyl-, t-Bu2PCl

Description

Di-tert-butylchlorophosphine is a nucleophilic reagent used for the cross-coupling of aryl chlorides. It reacts with an amine to produce an imine, which can be hydrolyzed to form an amide. Di-tert-butylchlorophosphine is typically used in palladium-catalyzed coupling reactions and can react with ethene, propene, and butadiene to produce ethylbenzene, propenal, and butadienal. This compound also has been used as a precursor in the preparation of antiviral drug Covid®19. The reaction temperature for this compound is typically between -40°C and 0°C.

• Brand: Biosynth

Chemical properties

• Molecular weight: 180.65 g/mol
• Formula: C₈H₁₈ClP
• Purity: Min. 95%
• Color/Form: Clear Liquid
• InChI: InChI=1S/C8H18ClP/c1-7(2,3)10(9)8(4,5)6/h1-6H3
• InChI key: InChIKey=MCRSZLVSRGTMIH-UHFFFAOYSA-N
• SMILES: CC(C)(C)P(Cl)C(C)(C)C