1-(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)piperazine hydrochloride

CAS: 98224-03-4

Ref. 3D-FD156233

Product Information

• Name: 1-(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)piperazine hydrochloride
• Synonyms: 1,4-Benzodioxin, piperazine deriv., 1-(1,4-Benzodioxan-5-yl)piperazine, 1-(2,3-Dihydro-1,4-Benzodioxin-5-Yl)Piperazine Hydrochloride, 1-(2,3-Dihydro-1,4-benzodioxan-5-yl)piperazine, 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazine, 1-(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)piperazine, 4-(2,3-Dihydro-1,4-benzodioxin-5-yl)-1-piperazine, 4-(2,3-Dihydrobenzo[1,4]dioxin-5-yl)piperazine, Eltoprazina, Eltoprazina [Spanish], Eltoprazine [INN], Eltoprazinum, Eltoprazinum [Latin], N-(2,3-Dihydrobenzo[1,4]dioxin-5-yl)piperazine, Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-, Unii-510M006Ko6

Description

1-(2,3-Dihydrobenzo[b][1,4]dioxin-5-yl)piperazine hydrochloride (DBDFP) is a dopamine receptor agonist and 5-HT2 receptor antagonist that has been shown to have an effect on locomotor activity. DBDFP also acts as a synergistic drug with eltoprazine in rats and humans. This drug has been shown to inhibit the uptake of serotonin into nerve terminals by blocking the serotonin transporter. In addition, chronic administration of this drug has been shown to cause degeneration of neurons in the hippocampal formation by increasing the expression of proinflammatory cytokines such as IL-1β and TNFα.

• Brand: Biosynth

Chemical properties

• Molecular weight: 256.73 g/mol
• Formula: C₁₂H₁₇ClN₂O₂
• Purity: Min. 95%