2,5-Diamino-4,6-dichloropyrimidine

CAS: 55583-59-0

Ref. 3D-FD16293

Product Information

• Name: 2,5-Diamino-4,6-dichloropyrimidine
• Synonyms: 2,5-Pyrimidinediamine, 4,6-Dichloro-, 4,6-Dichloro-2,5-pyrimidinediamine, 4,6-Dichloropyrimidine-2,5-diamine, 4,6-Dichlorpyrimidin-2,5-diamin, NSC 176971

Description

2,5-Diamino-4,6-dichloropyrimidine is a biomolecule that is made of carbon, hydrogen, nitrogen, and chloride. It has been shown to inhibit cell growth in culture by reacting with malonic acid to form an oxidation product. This product can then react with trifluoroacetic acid to form a chlorinating agent which reacts reversibly with amine groups on the nucleobases in DNA. The reaction mechanism may be due to the ability of 2,5-Diamino-4,6-dichloropyrimidine to react with amino function and amide groups on nucleobases in DNA. 2,5-Diamino-4,6-dichloropyrimidine has also been shown to have anti-cancer activity against leukemia cells.

• Brand: Biosynth

Chemical properties

• Molecular weight: 179.01 g/mol
• Formula: C₄H₄N₄Cl₂
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C4H4Cl2N4/c5-2-1(7)3(6)10-4(8)9-2/h7H2,(H2,8,9,10)
• InChI key: InChIKey=ZXWGHENZKVQKPX-UHFFFAOYSA-N
• SMILES: Nc1nc(Cl)c(N)c(Cl)n1