Detanonoate

CAS: 146724-94-9

Ref. 3D-FD16348

Product Information

• Name: Detanonoate
• Synonyms: 2,2'-(Hydroxynitrosohydrazino)bis-ethanamineNOC-183,3-Bis(aminoethyl)-1-hydroxy-2-oxo-1-triazeneDiethylenetriamine/nitric oxide a dduct, 1,1-Bis(2-Aminoethyl)-2-Hydroxy-3-Oxotriazane, 1-Hydroxy-2-Oxo-3,3-Bis(3-Aminoethyl)-1-Triazene, 2,2'-(2-Hydroxy-3-Oxotriazane-1,1-Diyl)Diethanaminium, 2,2'-(Hydroxynitrosohydrazino)Bis-Ethamine, 2,2'-(Hydroxynitrosohydrazino)Bis-Ethanamine, 2,2′-(2-Hydroxy-2-nitrosohydrazinylidene)bis[ethanamine], 3,3-Bis(Aminoethyl)-1-Hydroxy-2-Oxo-1-Triazene, Deta Nonoate, Deta/No, Diethylamine NONOate, Diethylamine diazeniumdiolate, Diethylenetriamine Nonoate, Ethanamine, 2,2′-(2-hydroxy-2-nitrosohydrazinylidene)bis-, Ethanamine, 2,2′-(hydroxynitrosohydrazono)bis-

Description

Detanonoate is a cyclase inhibitor that can induce apoptosis and inhibit the production of pro-inflammatory cytokines. Detanonoate has been shown to be minimally toxic in cell culture studies and to have a minimal effect on enzyme activity. Detanonoate also has significant cytotoxicity against tumor cells, with minimal toxicity against normal cells. It also exerts an anti-inflammatory effect through its inhibition of toll-like receptor 4, which is involved in the inflammatory response. Detanonoate has been shown to decrease tumor growth by inhibiting matrix metalloproteinase-9 (MMP-9) activity, which may be due to its ability to inhibit mitochondrial membrane potential. Detanonoate is used for the treatment of bowel disease.

• Brand: Biosynth

Chemical properties

• Molecular weight: 163.18 g/mol
• Formula: C₄H₁₃N₅O₂
• Purity: Min. 95%
• Color/Form: White Powder