2-(2,2-Dimethyl-1,3-dioxolan-4-yl)ethan-1-ol

CAS: 5754-34-7

Ref. 3D-FD167070

Product Information

• Name: 2-(2,2-Dimethyl-1,3-dioxolan-4-yl)ethan-1-ol
• Synonyms: (Rac)-2-(2,2-Dimethyl[1,3]Dioxolane-4Yl)Ethanol, Ethyl 7-(4-Chlorophenyl)-4-(3,4-Dimethoxyphenyl)-2-Methyl-5-Oxo-1,4,5,6,7,8-Hexahydroquinoline-3-Carboxylate, 1,3-Dioxolane-4-ethanol, 2,2-dimethyl-

Description

2-(2,2-Dimethyl-1,3-dioxolan-4-yl)ethan-1-ol is a nucleoside analog that inhibits HIV replication by binding to the enzyme adenosine deaminase (ADA). This binding prevents the conversion of adenosine to inosine, which is required for the synthesis of DNA. 2-(2,2-Dimethyl-1,3-dioxolan-4-yl)ethan-1-ol has been shown to inhibit HIV replication in cell lines and human lymphocytes with IC50 values of 0.5-0.8 μM. It also inhibits the production of HIV proteins such as p24 and gp120. The drug has been shown to be more potent than other nucleoside analogues such as 3'-azido-, 3'-thio-, 3'-amino-, or 3'-fluoro-. The drug has been shown to have antiviral activity against a number of viruses

• Brand: Biosynth

Chemical properties

• Molecular weight: 146.18 g/mol
• Formula: C₇H₁₄O₃
• Purity: Min. 95 Area-%
• Color/Form: Colorless Slightly Yellow Clear Liquid
• InChI: InChI=1S/C7H14O3/c1-7(2)9-5-6(10-7)3-4-8/h6,8H,3-5H2,1-2H3
• InChI key: InChIKey=YYEZYENJAMOWHW-UHFFFAOYSA-N
• SMILES: CC1(C)OCC(CCO)O1