Product Information
Name:Domoic acid
Brand:Biosynth
Description:Domoic acid is a neurotoxin that has been shown to induce neuronal death in vitro and in vivo. Domoic acid inhibits the activity of ligand-gated ion channels, which increases the cytosolic Ca2+ concentration. This toxin also induces mitochondrial membrane potential loss, causing apoptosis. Domoic acid binds to the NMDA receptor and blocks glutamate binding. It also inhibits ATP synthase by competing with ADP for binding sites on the enzyme's F1 portion. Domoic acid has low potency as a neurotoxin because it does not readily cross the blood-brain barrier or enter cells via passive diffusion.
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Chemical properties
Molecular weight:311.33 g/mol
Formula:C15H21NO6
Purity:Min. 90 Area-%
Color/Form:Beige Powder
Technical inquiry about: Domoic acid
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