12,14-Dichlorodehydroabietic acid

CAS: 65281-77-8

Ref. 3D-FD168595

Product Information

• Name: 12,14-Dichlorodehydroabietic acid
• Brand: Biosynth
• Description: 12,14-Dichlorodehydroabietic acid is a nicotinic acetylcholine receptor agonist that has been shown to inhibit the uptake of calcium ions and reduce the calcium overload in cells. This agent is used as a chemical intermediate in the production of vitamin E. It has also been used as a treatment for cardiac arrhythmias and has been demonstrated to provide an inhibitory effect on protein synthesis. 12,14-Dichlorodehydroabietic acid is activated by hydrolysis and reacts with free fatty acids to form 12,14-dichlorohydroabietic acid. The reaction mechanism involves activation energies at ca2+ concentrations between 0.5mM and 1mM. A kinetic study found that activation energy increases with increasing concentration of calcium ions present in the solution.

Chemical properties

• Molecular weight: 369.33 g/mol
• Formula: C₂₀H₂₆Cl₂O₂
• Purity: Min. 95%