Diethanolamine fusidate

CAS: 16391-75-6

Ref. 3D-FD173301

Product Information

• Name: Diethanolamine fusidate
• Synonyms: (2Z)-2-[(3alpha,4alpha,5alpha,8alpha,9xi,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methylhept-5-enoic acid - 2,2'-iminodiethanol (1:1), (3alpha,8alpha,9beta,13alpha,14beta,16beta,17(Z))-16-(Acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid, compd. with 2,2'-iminobis(ethanol) (1:1), (4alpha,8alpha,9beta,13alpha,14beta,17Z)-16beta-Acetoxy-3alpha,11alpha-dihydroxy-29-nordammara-17(20),24-dien-21-oic acid, compound with 2,2'-iminodiethanol (1:1), 29-Nor-8α,9β,13α,14β-dammara-17(20),24-dien-21-oic acid, 3α,11α,16β-trihydroxy-, 16-acetate, compd. with 2,2′-iminodiethanol (1:1), (Z)-, 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-, compd. with 2,2′-iminobis[ethanol] (1:1), Ethanol, 2,2′-iminobis-, (3α,4α,8α,9β,11α,13α,14β,16β,17Z)-16-(acetyloxy)-3,11-dihydroxy-29-nordammara-17(20),24-dien-21-oate (salt)
• CAS: 16391-75-6

Description

Diethanolamine fusidate is an aminoglycoside antibiotic that inhibits protein synthesis in bacteria by binding to the ribosomes. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Diethanolamine fusidate has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. This drug also has anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

• Brand: Biosynth

Chemical properties

• Molecular weight: 621.84 g/mol
• Formula: C₃₅H₅₉NO₈
• Purity: Min. 95%