Dansyl acid

CAS: 4272-77-9

Ref. 3D-FD20785

Product Information

• Name: Dansyl acid
• Synonyms: 5-Dimethylaminonaphthalene-1-sulfonic acid5-(Dimethylamino)-1-naphthalenesulfonic acid
• Brand: Biosynth
• Description: Dansyl acid is a fatty acid that can be used as a fluorescent probe to study the binding of amines to receptors in human serum. Dansyl acid binds to amines by forming a covalent bond. It has been shown that the binding constants of dansyl acid are dependent on the pH, chloride concentration, and nitrogen atom content. The reaction mechanism of dansyl acid is proposed to involve an initial protonation step followed by nucleophilic attack. This process leads to a resonance-stabilized carbenium ion intermediate with two free electrons, which then quickly reacts with chloride ions or hydrochloric acid to form dansyl chloride or benzenesulfonic acid, respectively.

Chemical properties

• Molecular weight: 251.3 g/mol
• Formula: C₁₂H₁₃NO₃S
• Purity: Min. 95%
• InChI: InChI=1S/C12H13NO3S/c1-13(2)11-7-3-6-10-9(11)5-4-8-12(10)17(14,15)16/h3-8H,1-2H3,(H,14,15,16)
• InChI key: InChIKey=BBEQQKBWUHCIOU-UHFFFAOYSA-N
• SMILES: CN(C)c1cccc2c(S(=O)(=O)O)cccc12