Daunomycinone

CAS: 21794-55-8

Ref. 3D-FD20803

Product Information

• Name: Daunomycinone
• Synonyms: (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy- -5,12-naphthacenedione(+)-DaunomycinoneDaunomycin aglicone DaunorubicinoneEpirubicin Impurity B, (+)-Daunomycinone, (8S,10S)-8-Acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione, 5,12-Naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-, (8S-cis)-, 5,12-naphthacenedione, 8-acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-, (8S,10S)-, Daunomycin aglicone, Daunomycinon, Daunomycinone derivative, Daunorubicin aglycone, Daunorubicinone, Leukaemomycinone C, NSC 109351

Description

Daunomycinone is a chemical compound that belongs to the group of antitumor agents. It is used in cancer therapy and has been shown to inhibit protein synthesis, leading to cell death. Daunomycinone can be synthesized by reacting adriamycin with trifluoroacetic acid in the presence of an organic base. This reaction produces a daunomycinone molecule that has a hydroxyl group at one end and a carbonyl group at the other. The binding constants between daunomycinone and human serum proteins have been determined experimentally using molecular modeling techniques. Hydrogen bonding interactions are also present in this complex, which may account for its high affinity for proteins found in human serum.

• Brand: Biosynth

Chemical properties

• Molecular weight: 398.36 g/mol
• Formula: C₂₁H₁₈O₈
• Purity: Min. 95%
• Color/Form: Red Powder