Product Information
Name:Deacetyl vinorelbine
Controlled Product
Synonyms:
- O4-Deacetyl-3',4'-didehydro-4'-deoxy-C'-norvincaleukoblastineDesacetylnavelbineO-Deacetylnavelbine
Brand:Biosynth
Description:Deacetyl vinorelbine is a prodrug that is metabolized to its active form, vinorelbine. It is used in the treatment of cancer and lung cancer. Deacetyl vinorelbine is converted by hydrolysis to deacetylvinorelbine, which inhibits the enzyme topoisomerase II and blocks DNA synthesis, leading to cell death. Vinorelbine also inhibits cellular respiration by inhibiting mitochondrial cytochrome c oxidase and blocking electron transfer from cytochrome c to oxygen. The drug binds to human serum albumin with high affinity and has been shown to have a long half-life in humans due to its ability to bind tightly with proteins such as serum albumin. This binding prevents the drug from being eliminated through the kidneys or liver, prolonging its activity in the body.
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Chemical properties
Molecular weight:736.9 g/mol
Formula:C43H52N4O7
Purity:Min. 95%
Color/Form:Solid
Technical inquiry about: Deacetyl vinorelbine
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