(-)-3-Dehydro shikimic acid

CAS: 2922-42-1

Ref. 3D-FD20947

Product Information

• Name: (-)-3-Dehydro shikimic acid
• Synonyms: DHS, 5-dehydroshikimic acid, 1-cyclohexene-1-carboxylic acid, 4,5-dihydroxy-3-oxo trans
• Brand: Biosynth
• Description: (-)-3-Dehydro shikimic acid is a natural product that is an inhibitor of bacterial growth. It has been shown to inhibit the synthesis of aromatic amino acids, such as phenylalanine, tyrosine, and tryptophan from shikimate by binding to the enzyme 3-dehydroshikimate dehydrogenase (DHAS). The activity of DHAS is required for the production of other aromatic compounds in bacteria, such as protocatechuic acid. (-)-3-Dehydro shikimic acid also inhibits protein synthesis and polymerase chain reactions. This suggests that it may be a useful agent for treating bacterial infections. (-)-3-Dehydro shikimic acid has been shown to have pharmacokinetic properties that are similar to those of erythromycin and clindamycin, which are commonly used antibiotics.

Chemical properties

• Molecular weight: 172.14 g/mol
• Formula: C₇H₈O₅
• Purity: Min. 97 Area-%
• Color/Form: Powder