N-Demethyl olanzapine

CAS: 161696-76-0

Ref. 3D-FD21007

Product Information

• Name: N-Demethyl olanzapine
• Synonyms: 2-methyl-4-(1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine4'-DesmethylolanzapineDesmethylolanzapine, 10H-Thieno[2,3-b][1,5]benzodiazepine, 2-methyl-4-(1-piperazinyl)-, 2-Methyl-4-(1-Piperazinyl)-10H-Thieno-[2,3-b][1,5]Benzodiazepine, 2-methyl-4-(piperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine, 4'-Desmethylolanzapine, Desmethylolanzapine, Ly 170055, N-Demethylolanzapine, N-Desmethylolanzapine

Description

N-Demethyl olanzapine is a metabolite of olanzapine. It is primarily formed by the demethylation of olanzapine and its concentration in plasma can be used as an indicator of olanzapine use. N-Demethyl olanzapine has been shown to cause hepatic steatosis, which may affect the analytical method for determining this drug in human serum. This drug also has a number of side effects that are related to its pharmacokinetic properties, including interaction with other drugs, such as antipsychotics and antidepressants. The concentration-time curve for N-demethyl olanzapine can be measured using an electrochemical detector.

• Brand: Biosynth

Chemical properties

• Molecular weight: 298.41 g/mol
• Formula: C₁₆H₁₈N₄S
• Purity: Min. 95%
• Color/Form: Yellow Solid
• InChI: InChI=1S/C16H18N4S/c1-11-10-12-15(20-8-6-17-7-9-20)18-13-4-2-3-5-14(13)19-16(12)21-11/h2-5,10,17,19H,6-9H2,1H3
• InChI key: InChIKey=FHPIXVHJEIZKJW-UHFFFAOYSA-N
• SMILES: Cc1cc2c(s1)Nc1ccccc1N=C2N1CCNCC1