Deoxy corticosterone acetate

CAS: 56-47-3

Ref. 3D-FD21044

Product Information

• Name: Deoxy corticosterone acetate
• Synonyms: 21-(Acetyloxy)-pregn-4-ene-3,20-dione11-Deoxycorticosterone 21-acetate21-Acetoxy-3,20-diketopregn-4-ene, (8Xi,9Xi,14Xi)-3,20-Dioxopregn-4-En-21-Yl Acetate, 11-Deoxycorticosterone 21-acetate, 11-Deoxycorticosterone, acetate, 11-Desoxycorticosterone acetate, 21-(Acetyloxy)pregn-4-ene-3,20-dione, 21-Acetoxy-3,20-diketopregn-4-ene, 21-Acetoxypregn-4-en-3,20-dione, 21-Acetoxypregn-4-ene-3,20-dione, 21-Acetyloxypregn-4-ene-3,20-dione, 21-Hydroxypregn-4-ene-3,20-dione 21-acetate, 21-Hydroxypregn-4-ene-3,20-dione acetate, 3,20-Dioxopregn-4-En-21-Yl Acetate, 4-Pregnene-3,20-dione 21-acetate, 4-Pregnene-3,20-dione-21-ol acetate, Acetate, Acetate De Desoxycortone, Acetato De Desoxicortona, Arcort, Bio-Corten, Cortacet, Cortate, Cortenil, Cortesan, Cortexone acetate, Cortifar, Cortigen, Cortinaq, Cortiron, Cortivis, Cortixyl, DCA, DOC acetate, Decorten, Decortin, Decosteron, Decosterone, Decostrate, Deoxycorticosterone 21-acetate, Deoxycorticosterone Acetate, Deoxycortone acetate, Descorterone, Descotone, Desoxycorticosterone Acetate, Desoxycortonacetat, Desoxycortone Acetate, Doca, Dorcostrin, Doxo, Doxycamon, Krinocorts, Nsc 9567, Ocriten, Ocritena, Percorten, Percotol, Pregn-4-ene-3,20-dione, 21-(acetyloxy)-, Pregn-4-ene-3,20-dione, 21-hydroxy-, acetate, Primocort, Primocortan, Sincortex, Steraq, Syncort, Syncorta, Syncortyl, Unidocan

Description

Deoxy corticosterone acetate is a synthetic analogue of the natural compound corticosterone. It has been shown to cause liver lesions, cardiac effects, and hypertension in laboratory animals. Deoxy corticosterone acetate binds to dinucleotide phosphate and prevents its conversion into cytosolic calcium. This interaction inhibits the phosphorylation of myocardial proteins and reduces the production of ATP in heart muscle cells. The binding of deoxycorticosterone acetate to DNA is also an important factor in its toxicity.

• Brand: Biosynth

Chemical properties

• Molecular weight: 372.5 g/mol
• Formula: C₂₃H₃₂O₄
• Purity: Min. 97 Area-%
• Color/Form: White Off-White Powder
• InChI: InChI=1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1
• InChI key: InChIKey=VPGRYOFKCNULNK-ACXQXYJUSA-N
• SMILES: CC(=O)OCC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C