Product Information
Name:Descarbamoyl cefuroxime
Synonyms:
- (6R,7R)-7-[[(2Z)-2-(2-Furanyl)-2-(methoxyimino)acetyl]amino]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxyli c acid
Brand:Biosynth
Description:Descarbamoyl cefuroxime is a prodrug that is hydrolyzed in vivo to cefuroxime, its active form. It can be prepared by acylation of cefuroxime with an organic acid chloride, such as acetyl chloride or propionyl chloride. The reaction is catalyzed by a strong base, such as sodium hydride or potassium tert-butoxide. Descarbamoyl cefuroxime has been shown to be effective against Staphylococcus aureus and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. This drug has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.
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Chemical properties
Molecular weight:381.36 g/mol
Formula:C15H15N3O7S
Purity:Min. 95%
Technical inquiry about: Descarbamoyl cefuroxime
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