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N-Deshydroxyethyl dasatinib
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N-Deshydroxyethyl dasatinib

CAS: 910297-51-7

Ref. 3D-FD21202

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Estimated delivery in United States, on Wednesday 15 Jan 2025

Product Information

Name:
N-Deshydroxyethyl dasatinib
Synonyms:
  • N-(2-Chloro-6-methylphenyl)-2-[[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl]amino]-5-thiazolecarboxamideDasatinib metabolite M4
Description:

Dasatinib is a multi-kinase inhibitor that is used in the treatment of acute lymphoblastic leukemia. It is metabolized by the cytochrome P450 enzyme CYP3A4, which may lead to an increase in the plasma concentrations of dasatinib when it is coadministered with CYP3A4 substrates such as rifampicin or phenytoin. Dasatinib also undergoes glucuronidation and sulfation, which are metabolic pathways that may contribute to its elimination from the body. The pharmacokinetic properties of dasatinib have been studied in healthy volunteers and patients with acute lymphoblastic leukemia. These studies showed that dasatinib has a half-life of about 12 hours and a clearance rate between 0.076 - 0.105 L/h/kg. The pharmacokinetic study also found that dasatinib levels were higher in patients who had received chemotherapy than those who had not before administration of

Notice:
Our products are intended for lab use only. For any other use, please contact us.
Brand:
Biosynth
Long term storage:
Notes:

Chemical properties

Molecular weight:
443.95 g/mol
Formula:
C20H22ClN7OS
Purity:
Min. 95%
MDL:
Melting point:
Boiling point:
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Density:
Concentration:
EINECS:
Merck:
HS code:

Hazard Info

UN Number:
EQ:
Class:
H Statements:
P Statements:
Forbidden to fly:
Hazard Info:
Packing Group:
LQ:

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