N-Desisopropyl metoprolol

CAS: 74027-60-4

Ref. 3D-FD21207

Product Information

• Name: N-Desisopropyl metoprolol
• Synonyms: 1-Amino-3-[4-(2-methoxyethyl)phenoxy]-2-propanolH 98/52
• Brand: Biosynth
• Description: N-Desisopropyl metoprolol is a chiral derivatized metoprolol that is used as a drug-development strategy for the treatment of cardiovascular diseases. It has been shown to have pharmacokinetic properties and drug–drug interactions comparable to those of the parent drug, metoprolol. N-Desisopropyl metoprolol has been shown to be metabolized by CYP2D6, which results in an increased half-life and decreased clearance. The fluorescence from N-desisopropyl metoprolol can be measured using fluorimeter techniques and provides useful information about its metabolism.

Chemical properties

• Molecular weight: 225.28 g/mol
• Formula: C₁₂H₁₉NO₃
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C12H19NO3/c1-15-7-6-10-2-4-12(5-3-10)16-9-11(14)8-13/h2-5,11,14H,6-9,13H2,1H3
• InChI key: InChIKey=XJWXVDJGNOHFLR-UHFFFAOYSA-N
• SMILES: COCCc1ccc(OCC(O)CN)cc1