4,6-Diamino-2-thiopyrimidine

CAS: 1004-39-3

Ref. 3D-FD21454

Product Information

• Name: 4,6-Diamino-2-thiopyrimidine
• Synonyms: 4,6-Diamino-2(1H)-pyrimidinethione4,6-Diamino-2-pyrimidinethiol2-Mercapto-4,6-diaminopyrimidine, 2(1H)-Pyrimidinethione, 4,6-Diamino-, 2-Mercapto-4,6-diaminopyrimidine, 2-Pyrimidinethiol, 4,6-diamino-, 2-Thio-6-aminocytosine, 4,6-Diamino-1,2-dihydro-2-thioxopyrimidine, 4,6-Diamino-1H-pyrimidine-2-thione, 4,6-Diamino-2(1H)-pyrimidinethione, 4,6-Diamino-2-pyrimidinethiol, 4,6-Diamino-2-thiouracil, 4,6-Diaminopyrimidine-2-thione, 4,6-diaminopyrimidine-2(1H)-thione, NSC 1586, NSC 680831, 4,6-Diamino-2-mercaptopyrimidine

Description

4,6-Diamino-2-thiopyrimidine is a glycosidic bond that has been shown to inhibit the growth of bacteria in cell culture. It has also been shown to have an anticoagulant effect on human serum. The molecular weight of heparin is typically between 5000 and 15000 Da. In this study 4,6-Diamino-2-thiopyrimidine was found to be the most potent inhibitor of heparinase I activity with an IC50 of 1.5 mM. This compound is a trifluoroacetate salt that has a neutral pH and low solubility in water. It can be detected by electrochemical impedance spectroscopy (EIS). Hydrolysis by hydrochloric acid yields 4,6-diamino-2-thiopyrimidine trifluoroacetic acid as the only product. The chemical name for this substance is 4,6 diamino 2 thiop

• Brand: Biosynth

Chemical properties

• Molecular weight: 142.18 g/mol
• Formula: C₄H₆N₄S
• Purity: Min. 95%
• Color/Form: Powder
• InChI: InChI=1S/C4H6N4S/c5-2-1-3(6)8-4(9)7-2/h1H,(H5,5,6,7,8,9)
• InChI key: InChIKey=QCAWOHUJKPKOMD-UHFFFAOYSA-N
• SMILES: Nc1cc(N)[nH]c(=S)n1