2,4-Diamino-6-hydroxy-5-nitropyrimidine
CAS:
Ref. 3D-FD21462
1g
186.00€
2g
315.00€
250mg
134.00€
500mg
150.00€
Product Information
Name:2,4-Diamino-6-hydroxy-5-nitropyrimidine
Synonyms:
- 2,6-Diamino-5-nitroso-4-pyrimidinolNsc44924
Brand:Biosynth
Description:2,4-Diamino-6-hydroxy-5-nitropyrimidine is an anticancer agent that has been shown to be effective against both bone and colorectal cancers. It inhibits the growth of cancer cells by inducing caspase-independent cell death, which occurs in a pd-l1 dependent manner. This agent also has minimal toxicity in vitro, as it induces cell lysis at high concentrations. 2,4-Diamino-6-hydroxy-5-nitropyrimidine is not active against normal cells.2,4-Diamino-6-hydroxy-5-nitropyrimidine induces mitochondrial membrane depolarization and mitochondrial membrane potential loss in a dose dependent manner. These effects are likely responsible for the induction of caspase independent cell death seen with this drug.
Notice:Our products are intended for lab use only. For any other use, please contact us.
Chemical properties
Molecular weight:171.11 g/mol
Formula:C4H5N5O3
Purity:Min. 95%
Color/Form:Yellow Powder
Technical inquiry about: 2,4-Diamino-6-hydroxy-5-nitropyrimidine
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