7H-Dibenzo[c,g]carbazole

CAS: 194-59-2

Ref. 3D-FD21527

Product Information

• Name: 7H-Dibenzo[c,g]carbazole
• Synonyms: 3,4:5,6-Dibenzocarbazole, 7-aza-7H-dibenzo[c,g]fluoreneNSC 87519, 3,4:5,6-Dibenzocarbazole = 7-Aza-7H-dibenzo[c,g]fluorene, 7-Aza-7H-dibenzo[c,g]fluorene, NSC 87519

Description

7H-Dibenzo[c,g]carbazole is a carcinogen that is formed when polycyclic aromatic hydrocarbons (PAHs) react with DNA. It can bind to nuclear DNA and activate the genotoxic pathway. The carcinogenic potential of 7H-dibenzo[c,g]carbazole has been studied using a model system of cultured human skin cells. This chemical has been shown to induce liver lesions in rats and to have genotoxic effects in vitro. 7H-Dibenzo[c,g]carbazole induces apoptosis by inhibiting protein synthesis and blocking the activation of caspases. 7H-Dibenzo[c,g]carbazole also inhibits the activity of cytochrome P450 enzymes involved in drug metabolism by binding to their heme moiety.

• Brand: Biosynth

Chemical properties

• Molecular weight: 267.32 g/mol
• Formula: C₂₀H₁₃N
• Purity: Min. 95%
• InChI: InChI=1S/C20H13N/c1-3-7-15-13(5-1)9-11-17-19(15)20-16-8-4-2-6-14(16)10-12-18(20)21-17/h1-12,21H
• InChI key: InChIKey=STJXCDGCXVZHDU-UHFFFAOYSA-N
• SMILES: c1ccc2c(c1)ccc1[nH]c3ccc4ccccc4c3c12